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Silver Sulfadiazine Cream - Uses, Side Effects, and More

Silver Sulfadiazine Cream – Uses, Side Effects, and More

Table of Contents

What is silver sulfadiazine cream used for?

Patients with severe burns use it along with other treatments to prevent and treat wound infections. Silver sulfadiazine keeps bacteria from growing on open wounds. This reduces the possibility of the bacteria spreading to nearby skin or blood (sepsis). Silver sulfates are a sulfa antibiotic; they cannot be given to premature or newborn babies during the first 2 months of life due to the possibility of side effects.

What is silver sulfadiazine cream used for?

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1 Silver Sulfadiazine Cream: How to Use

Only the skin should be treated with this medication. If your doctor says you can, don’t use this around your eyes.

The health care provider will clean and remove dead tissue from the wound in order to aid in the healing process.

In order to apply this medication properly, you should wear sterile gloves and use sterile tools, as instructed by your doctor, generally once or twice a day. It is recommended to place a layer of medication approximately one-sixteenth of an inch thick (1-2 millimeters) or as directed. Always apply the cream directly to the wound. It is possible to put clothing over the cream, but only if necessary. Reapply the cream immediately if it has rubbed off the wound. Reapply the cream after hydrotherapy as well.

As a general rule, the wound is treated until it has healed or until a skin graft can be performed.

It is important to take this medicine regularly in order to reap the most benefits. It should be taken at the same time every day.

If your condition doesn’t go away or gets worse, tell your doctor.

silver sulfadiazine 1 % topical cream

Silver sulfadiazine 1 % topical cream

Color: white

This medicine is a white, cream

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Side Effects of Silver Sulfadiazine Cream:-

There may be some discomfort, burning, or itching associated with the treatment. Discoloration of the skin and mucous membranes, including the gums. If any of these effects last or get worse, tell your doctor or pharmacist.

Your doctor prescribed this medicine because they think the benefits outweigh the risks. Few people experience serious side effects from this medication.

In the rare event that any of these serious side effects occur, tell your doctor right away: signs of infection (such as sore throats that don’t go away, fevers, chills), easy bruising/bleeding, signs of anemia (In addition to fatigue/weakness, signs of kidney problems (such as changes in the amount of urine, pink/bloody urine), signs of liver problems. (such as nausea that does not improve, stomach/abdominal pain, vomiting, dark urine, yellowing eyes/skin), mental/emotional changes seek medical help as soon as possible.

Side Effects of Silver Sulfadiazine Cream:-

With this drug, you’re unlikely to get a severe allergic reaction. Symptoms of allergic reactions include rash, itching/swelling (especially of the face, tongue, and throat), severe dizziness, and difficulty breathing.

I may have missed some side effects. You should talk to your doctor or pharmacist about any other side effects.


Let your doctor or pharmacist know if you’re allergic to silver sulfadiazine; or any other sulfa antibiotics (like sulfamethoxazole); or if you have any other allergies. There could be inactive ingredients that cause allergies. Check with your pharmacist.

Talk to your doctor if you have a G6PD deficiency, kidney problems, liver problems, or a low white blood count.

Let your doctor or dentist know everything you take (including prescription drugs, over-the-counter medicines, and herbal remedies).

This medication shouldn’t be used during pregnancy unless it’s absolutely necessary. Due to potential harm to the unborn baby, this medication should not be taken near the due date. Ask your doctor.

We don’t know if this medication passes into breast milk. However, similar drugs pass into breast milk, and they can harm nursing infants (like those with jaundice, high blood bilirubin levels, G6PD deficiency) who are ill, premature, or under 2 months old. You shouldn’t breastfeed a baby with these conditions when you’re taking this drug. Talk to your doctor first.


Other drugs and herbal products can change the effects of some drugs. If you do this, you may end up with serious side effects or your medication may stop working. Sometimes these drug interactions happen, but not always. Doctors and pharmacists can often prevent or manage drug interactions by changing how you take your medicines or by closely monitoring you.

Before you start taking this product, tell your doctor and pharmacist all the things you take (including prescriptions, nonprescription, and herbal supplements). When you’re using this, don’t start, stop, or change any other medicines you’re taking.

There are a few products that may interact with this drug: cimetidine, sodium sulfacetamide containing skin products, enzymes that break down dead skin and tissue from burns and wounds (like collagenase, papain, trypsin).

In some brands of this drug, propylene glycol can interfere with lab tests, giving false results. Make sure all your doctors and lab personnel know you’re taking it.

There might be some drug interactions not covered in this document. Write them down. Let your doctor and pharmacist know about this list so you’ll be less likely to have serious medication issues.

Overdose Issues:-

You shouldn’t swallow this medicine. Call 911 if someone has overdosed and is passing out or having trouble breathing. If not, call a poison control center. You can reach your local poison control center at 1-800-222-1222. In Canada, call the poison control center in your province.

Don’t give it to anyone else.

Check for side effects by getting a blood test, white blood cell count, kidney function test, etc. Talk to your doctor.

Make sure you keep all your medical appointments.

Didn’t get your dose:-

You should use it right away if you forget. As your doctor tells you, you should keep it on your wounds at all times.


Store US products between 59-86 degrees Fahrenheit (15-30 degrees Celsius). Do not place them in the bathroom.

It should be stored between 46 and 77 degrees F (8 and 25 degrees C). To maintain sterility, 250-gram and 500-gram Canadian jars should be discarded within 24 hours of opening. Canadian tubes should be thrown away seven days after opening. Avoid storing them in the bathroom.

Children and pets shouldn’t have access to medicines.

Pour them into the drain if you’re not sure. Throw them out when they’re expired. Any questions about dumping your medications can be asked to your pharmacist if you have any.

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